RAD was shown to have activity in human tumor cell lines originating from lung, breast, prostate, colon, kidney, melanoma and glioblastoma. RAD was.
Official Title: Phase II Trial of RAD Plus Carboplatin in Patients With Triple-Negative Metastatic Breast Cancer. Study Start Date: June Actual Primary.
The combination of gefitinib and RAD inhibits growth of HER2 overexpressing breast cancer cells and tumors irrespective of trastuzumab.
Anticancer Res. Sep;31(9) The mTOR inhibitor RAD sensitizes tumor cells to the cytotoxic effect of carboplatin in breast cancer in vitro.
Afinitor (everolimus), formerly known as RAD, is a macrolide antibiotic used to treat pancreatic neuroendocrine tumours, gastric cancer and breast cancer.